富硒发芽糙米调节小鼠血脂和保护肝组织作用的研究.docVIP

富硒发芽糙米调节小鼠血脂和保护肝组织作用的研究 胡玲玲1,2，李春阳1,2*，曾晓雄1，吴建苏3 （1. 南京农业大学食品科技学院，江苏省南京市 210095；2. 江苏农业科学院农产品加工所，江苏省南京市 210014；3. 南京远望富硒农产品有限责任公司，江苏省南京市 211500） 摘要：本文以小鼠为实验对象，研究富硒发芽糙米（含硒0.870mg/kg）对小鼠血脂水平和肝组织的影响。结果表明：与模型组小鼠相比，当给小鼠喂食含富硒发芽糙米25%的高脂饲料时，小鼠血清TC、TG、LDL-C水平和体重增长比分别下降56.80%、77.53%、55.84%、3.75%，HDL-C水平升高74.03%；肝组织中GOT、GPT、MDA水平分别降低65.66%、38.60%、50.32%，GSH、SOD水平和肝指数分别升高193.98%、187.33%、31.46%；同时，小鼠肝脏组织较紧密，色泽红且被膜光滑。结论表明，本实验中的富硒发芽糙米具有调节小鼠血脂水平，控制小鼠体重增长及保护组织的作用。 关键词：富硒发芽糙米；发芽糙米；血脂；肝组织；保护作用 Effects of selenium-enriched germinated brown rice on blood lipid and liver protection in mice HU Ling-ling1,2，LI Chun-yang1,2*，ZENG Xiao-xiong1，WU Jian-su3 Nanjing Agriculture University,Food College,Nanjing 210095,China；2. Institute of Agro-Food Science and Technology,Jiangsu Academy of Agriculture Science,Nanjing 210014,China；3.Jiangsu Yuanwang Selenium-rich Agricultural Products Co,Ltd.Nanjing 211500,China) Abstract: This study investigated the selenium-enriched germinated brown rice influence on hypolipidemic and liver protection in mice. The results demonstrated that: compared with the HFD group, eating high fat forage contained 25% selenium-enriched germinated brown rice mice serum TC, TG, LDL-C and weight growth rate were respectively decreased 56.80%, 77.53%, 55.84%, 3.75%, HDL-C were increased 74.03%; GOT, GPT, MDA in liver tissue were respectively decreased 65.66%、38.60%、50.32%, GSH，SOD and the liver index were respectively increased 193.98%、187.33%、31.46%. Also the high dose groups’ liver tissue were more close, red and smooth. The result showed that selenium-enriched germinated brown rice (contain 0.870 mg/kg selenium) possess the efficacy of lipid-lowering, controlling weight and protecting the liver. Key words: selenium-enriched germinated brown rice; germinated brown rice; blood lipid; liver tissue; protection effects 随着生活水平的提高，人们的饮食结构发生改变，导致摄入的胆固醇、脂肪等过多，高血脂症、脂肪肝的发病率逐年增高，高血脂症发病率达21.4%［1］，如不及时控制可能会导致中风、肝癌等疾病［2］。现代营养学研究表明［3-4］，富硒发芽糙米具有降低血清胆固醇，增强机体抗氧化功能的功效［5］。 谭俊峰等［6］对GABA超微绿茶粉进行