[医学]医学英文论文写作U3-Introduction.pptVIP

ICMJE’s uniform requirements Provide a context or background for the study (i.e., the nature of the problem and its significance). State the specific purpose or research objective of, or hypothesis tested by, the study or observation. Both the main and secondary objectives should be made clear, and any pre-specified subgroup analyses should be described. Give only strictly pertinent references and do not include data or conclusions from the work being reported. ICMJE’s uniform requirements What readers and editors are looking for in our introduction: background and rationale. Introduction What happened at the beginning? How did ideas develop? How did new techniques help? What are the existing gaps to be filled in by your own work? Move 1: Presenting background information Move 1 consists of a few persuasive, anecdotal or didactic (instructional) sentences. Because we are talking about what is known now, the present verb tenses predominate. Move 1: Presenting background information TC-1 Is a Novel Tumorigenic and Natively Disordered Protein Associated with Thyroid Cancer Thyroid cancer is the most common endocrine malignancy, accounting for 90% of all of the endocrine cancers. The incidence varies substantially around the world, with rates continuing to increase in many countries during the past several decades. Papillary thyroid carcinoma is the most common histologic type. In general, these are slow-growing malignancies with good prognoses; however, for a subset of patients, more aggressive metastatic disease develops. Treatment options vary from high-dose radioiodine treatment to surgical resection of metastatic foci, and although effective therapy reduces morbidity and mortality, some continue to have persistent aggressive disease. Move 1: Presenting background information Furthermore, there is frequent use of locative and temporal adverbials that help to contextualize the paper for the reader. Example: Between 1990 an