心房颤动的治疗新的循证医学证据——英文课件演示文稿.pptVIP

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心房颤动的治疗新的循证医学证据——英文课件演示文稿.ppt

演示文稿演讲PPT学习教学课件医学文件教学培训课件

              Management of Atrial Fibrillation: Update in the EBM proof;Prevalence of AF is increasing;Miyasaka.Circulation.2006:119;Prevalence %;Incidence ‰;Identified AF:the tip of the iceberg;Risk for stroke increased in lone AF;Meta-analysis: antithrombotic therapy of AF;Real world of warfarin in the elderly;HR for ICH was 4.06 for Asians;Anticoagulation in clinical practice;Rivaroxaban;Prospective RIKS-HIA 60764 pts,AF 21459 pts,CHF 22345 pts,AF+CHF16960 pts F/U 1 yr Higher mortality rate in AF without CHF pts taking digoxin (RR1.42) Similar mortality rate in CHF or AF+CHF pts with or without digoxin ;Hallberg.Euro J Clin Pharmacol,2007,959;Adverse effects of oral amiodarone;Nichol G . Heart. 2002:535 J Am Coll Cardiol. 2003:20;Amiodarone increased mortality of HF SCD-HeFT研究;Dronedarone:Substitution of amiodarone?;64.1%;Catheter ablation is superior to antiarrhythmic durg;APAF Trial;Oral.NEJM.2006:934;Catheter ablation decrease the incidence of stroke;Pappone . JACC.2003:185;Pappone . JACC.2003:185;No risk factor: ASA 81- 325mg One moderate risk factor:ASA 81- 325mg or warfarin Any high risk factor or more than one moderate risk factor: warfarin;Amiodarone=Ablation !;Indications for catheter ablation;AF Ablation as first-line therapy? (Catheter Ablation vs. Antiarrhythmic Drug Therapy for Atrial Fibrillation Trial, CABANA);Thank You!

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