心房颤动的治疗新的循证医学证据——英文课件演示文稿.pptVIP

　　　　　　　　　　　　　 Management of Atrial Fibrillation： Update in the EBM proof;Prevalence of AF is increasing;Miyasaka.Circulation.2006:119;Prevalence %;Incidence ‰;Identified AF：the tip of the iceberg;Risk for stroke increased in lone AF;Meta-analysis: antithrombotic therapy of AF;Real world of warfarin in the elderly;HR for ICH was 4.06 for Asians;Anticoagulation in clinical practice;Rivaroxaban;Prospective RIKS-HIA 60764 pts，AF 21459 pts,CHF 22345 pts,AF+CHF16960 pts F/U 1 yr Higher mortality rate in AF without CHF pts taking digoxin (RR1.42) Similar mortality rate in CHF or AF+CHF pts with or without digoxin ;Hallberg.Euro J Clin Pharmacol,2007,959;Adverse effects of oral amiodarone;Nichol G . Heart. 2002:535 J Am Coll Cardiol. 2003:20;Amiodarone increased mortality of HF SCD－HeFT研究;Dronedarone：Substitution of amiodarone？;64.1%;Catheter ablation is superior to antiarrhythmic durg;APAF Trial;Oral.NEJM.2006:934;Catheter ablation decrease the incidence of stroke;Pappone . JACC.2003:185;Pappone . JACC.2003:185;No risk factor： ASA 81- 325mg One moderate risk factor：ASA 81- 325mg or warfarin Any high risk factor or more than one moderate risk factor: warfarin;Amiodarone＝Ablation ！;Indications for catheter ablation;AF Ablation as first-line therapy?(Catheter Ablation vs. Antiarrhythmic Drug Therapyfor Atrial Fibrillation Trial, CABANA);Thank You!