中药对冠心病的多靶点治疗演示文稿.pptVIP

Aggregation of platelets into a thrombus Platelets Endothelial cells Subendothelial space Platelets adhering to subendothelial space Platelet thrombus 血小板聚集和活化 Normal platelets in flowing blood Platelets adhering to damaged endothelium and undergoing activation Aspirin NSAIDs ADP receptor COX-1 TXA2 GPIIb - IIIa Signalling pathways ADP receptor antagonists Clopidogrel THROMBIN receptor Thrombin inhibitors II Fibrinogen Phosphodiesterase inhibitors dipyridamole Fibrinogen Receptor Antagonists AA Targets for anti-platelet therapy Platelet-fibrinogen interaction Platelet aggregatio