毕业设计（论文）-上转换纳米材料在生物医学中的应用与研究进展精选.docxVIP

上转换纳米材料在生物医学中的应用与研究进展摘要:ⅠAbstractⅡ第1章 高对比成像11.1 高对比度成像的应用11.2 体内外毒性评价3第2章 细胞成像5第3章 整体发光成像63.1. 被动成像63.2. 主动靶向73.3. 深层组织成像8第4章 光学层析成像10第5章 多模态成像125.1. 上转换材料在磁共振成像（MRI）中的应用125.2. 上转换材料在X射线计算机断层扫描（CT）中的应用135.3. 上转换材料在正电子发射断层扫描（PET）中的应用145.4. 上转换材料在多重成像中的应用15结 论17致 谢18参考文献19上转换纳米材料在生物医学的应用与研究进展摘要:上转换纳米材料在生物医学中具有良好的应用前景，跟传统的荧光材料比较，具有荧光背景低，穿透能力强，对生物组织伤害度低等优点，是目前生物医学领域研究的重要材料之一。除此之外，上转换材料还具备良好的光化学性能，使用时间较长，并且有良好的生物兼容性等特点，能够推动检测及治疗技术的研究与发展。本文主要对于上转换纳米材料在生物医学上的应用进行详细研究与调查，探索上转换纳米材料在各种应用上所面临的问题，进而提出建设性的意见。主要针对目前上转换纳米材料在肿瘤治疗中的应用现状及研究进展进行综合评述及阐述，对上转换纳米材料各种用于肿瘤治疗的方法及各自的优缺点进行了阐述分析，为其进一步研究和应用奠定基础。关键词:生物医学 上转换纳米材料 荧光材料 肿瘤治疗 研究进展Upconversion Nanoparticles: Design, Nanochemistry, and Applications in Theranostics Abstract：Upconversion nanomaterials based on rare earth show a good application prospect in cancer therapy. Compared with traditional fluorescent materials, upconversion nanomaterials have many advantages, such as the near infrared laser excited, almost no fluorescent background, remarkable deeper tissue penetration and low biological tissue damage, which lead to a hot research material in biomedical now. Meanwhile, upconversion materials, due to the good photochemical properties, long service life, good biological compatibility and other advantages, promote the development of detection and treatment technology. This work focuses on the application of upconversion nanomaterials in biomedical, and the study of upconversion nanomaterials in the application still have problems, which put forward some advices on current opinion. Application and research of upconversion nanomaterials in the treatment of tumor development are reviewed. In this paper, the advantages and disadvantages of the methods for the treatment of tumor were analyzed, which provided a new potential idea for further research and clinical application.Keywords: theranostics; upconversion nanoparticles; fluorescent materials; cancer therapy; applications in theranostics 高对比成像1.1 高对比度成像的应用将成像和治疗联合起来使用于未来个性化药物是生物医学以及