微RNA-133和心肌肥厚钙调磷酸酯酶控制的相互抑制(英文)精选.pptVIP

Background Calcineurin/NFAT pathway induces Cardiac Hypertrophy Calcineurin activation in cardiac hypertrophy Decreased miR-133 expression in cardiac hypertrophy Overexpression of miR-133 inhibits cardiac hypertrophy Inhibition of miR-133 induces cardiac hypertrophy 1. Calcineurin-Dependent Cardiac Hypertrophy 1. Calcineurin-Dependent Cardiac Hypertrophy 1.Calcineurin-Dependent Cardiac Hypertrophy 2. Calcineurin Activation in cardiac hypertrophy * * Reciprocal Repression between MicroRNA-133 and Calcineurin Controls Cardiac Hypertrophy: A Novel Mechanism for Progressive Cardiac Hypertrop