炎症性肠病：面临的问题与挑战.ppt

炎症性肠病：面临的问题与挑战 Increasing cumulative number of ulcerative colitis and Crohn’s disease patients in Japan during a 17-year period according to the national registry maintained by the Ministry of Health, Labor and Welfare of the Japanese government Age- and sex-adjusted annual incidence ofCD and UC in the Songpa-Kangdongdistrict, Seoul, 1986–2005. Annual Incidence of IBD in Hong Kong UC (3100 cases) Time trend (data from 7 hospitals) IBD — 我国面临的问题与挑战 流行病学：近年病例数增长很快，但缺乏基于社区人口的流行病学研究，缺乏确切的患病率、发病率 中国处于一个流行病学研究的黄金时期 生活模式发生巨大变化：冰箱（冷链学说） 食物解构：西方化 IBD — 我国面临的问题与挑战 遗传易感性 中国（亚洲）与西方明显不同：NOD2 易感基因的