离体培养细胞的力学方法-polyuira.pdfVIP

J Biomed Eng 　2002; 19( 2) ∶324～ 328　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　 * 1 1,△ 2 1 白　灵　樊瑜波 　张　明　综述　陈君楷　审校 1(四川大学 建筑与环境学院生物力学四川省重点实验室,成都　610065) 2(香港理工大学 复康科技中心,香港 龙) 　　　, ,。 ,: 、、 , 。 　　　 Experimental Methods for Mechanically Stimulating the Cells in Vitro 1 1,△ 1 Bai Ling　Fan Yubo 　Zhang Ming　Chen Junkai 1(B iomech anics L abor atory , Sich uan Univ ersity , Cheng du　610065) 2(R eh abil ita tion Eng i neerin g Centre , The Hon g K on g P oly tech nic Un iv ersity , Kow loon H ong K ong ) 　　Abstract　 Cellular m echanics is a branch of tissue engineering and cellular engineering. As one of the impor tant method, loading different mechanical stimuli to culturing cells in vitro so as to study the influence that the stress has on th e cells is one of the important fields of cellular mechanics This paper review s th e experim ental. methods for mechanically stimulating the cells in vitro, according to the different loading modalities, the methods can be categorized into micropipette aspiration, compression loading, substrate distention,fluid shear, etc. And it also points out th eir advantages and disadvantages. 　 　　 　　 Key words Cells in vit ro Mechanical force Cellular mechanics 。 / 1　　 、, , 。 。 , , [1] Glucksmann , 、, , , [ 2] 。