多发性硬化英文-课件.pptxVIP

Multiple Sclerosis and Currently Available Treatments in the USMichelle Rainka, Pharm.D., CCRPDent InstituteUniversity at Buffalomailto:mrainka@mrainka@mailto:mmrainka@mmrainka@Copyright ?: Reproduction of these slides is prohibited without permission of the authorMultiple Sclerosis“Multiple”- multiple areas of lost myelin“Sclerosis”- ScarringMS is a chronic autoimmune inflammatory diseaseAffects Central Nervous System (brain, spinal chord and optic nerves)International Journal of MS CareMultiple SclerosisMultiple SclerosisA chronic, autoimmune disease Affects central nervous system ? the myelin sheath covering of nerve fibers in the brain and spinal cordImpairs the nerves ability to send electrical impulsesMS StatisticsApproximately 400,000 Americans are diagnosed with MS Affects 2.5 million people worldwideSymptom onset and diagnosis occur typically between the ages of 20-502.5:1 women:man ratioPeople of Northern European descent are afflicted most commonlyMore common above 40° latitude in areas like western New York.Women are 2 times more likely to get the disease (i.e. 2 women for every 1 men)More common in Northern European descendants than any other raceFound in people who live in temperate climatesOnset occurs between ages of 20 and 40/what-is-ms/statistics/Symptoms of MSFatigueSexual DysfunctionSpeechSwallowingAbnormal sensationsTinglingNumbnessSensitivity to heatBladder and bowel problemsFrequencyLoss of controlMuscle weaknessVisual symptomsBlurry visionDouble visionUnsteady gait/balance issuesPain/ParesthesiasEmotional/Cognitive disturbancesShort term memory lossInability to concentrateMultiple Sclerosis Kurtzke disability status scale1 No disability minimal neurologic sign2 Minimal disability - slight weakness or stiffness, mild disturbance of gait or mild visual disturbance3 Moderate disability - monoparesis (partial or incomplete paralysis affecting one or part of one extremity) mild hemiparesis (slight paralysis affecting one side of body) moderat