低分子肝素防治下肢深静脉血栓形成研究进展.pdf

2009 A ug30 ( 4) J L iaon ing M ed ica l U n iversity 373 李江涛, 齐尚锋 (, 2500 14) : 下肢深静脉血栓形成 ( DVT ) 是骨科手术病人最严重的并发症之一, 临床研究发现低 子肝素 ( LM WH ) 其抗血栓作用优于低剂量的普通肝素 ( U nfractionated H ep ar in, U FH ) , 而抗凝作用无明显差别, 对出血和 血小板功能无明显影响, 在治疗已发 DVT 病例的有效性和安全性也优于一般药物 : 低 子肝素 下肢深静脉血栓形成 防治 : R 54 36 : A : 1674 - 0424 ( 2009) 04 - 0373- 0 3 Low M olecularW eight Heparin Applied in Prevention of Deep V enous Thrombosis L I Jiangtao, Q I Sh ang feng ( Shandong U niversity of T raditiona l Ch inese M edic ine, J inan 2500 14 China) Abstract: D eep venou s th rom bosis ( DVT ) is one o f the most seriou s comp lication s of orthop edic surgery pa tientsC lin ica l stu d ies h ave ind icated th at reg ard ing the anti- thrombotic effec t, low m o lecular w e ight hep ar in ( LMWH ) is supe rio r to low - dose un frac tionated hep arin ( U FH ) , and it h as no sign if ican t e ffect on plate let function and bleed ingM oreover, the efficacy and sa fe ty o f LMWH in the treatm ent of DVT cases are better th an genera l drugs K e words: low m o lecular w e ight hep ar in deep venous thrombosis preven tion ( deepveinthrombosis, 1 DVT ) , , 11 : , , , , , X a , , a 4 1, , , , : , , , 90% ( 30% , ~ 40% ), 1 ,