抗生素课件课件(英文精品) Infection in acute pancreatitis.pptVIP

Infection in acute pancreatitis Acute pancreatitis: Interstitial: 80% Necrotizing: 20% Infection dependent on - necrosis Extent of necrosis Sterile (n = 155) Infected ( n = 71) 30% (mild) 57 % 35 % 30 - 50% (mod) 22 % 23 % 50% (severe) 21 % 42 % Duration 1 – 2 weeks 50% 3 weeks 71% Pancreatic abscess 4 weeks Parameters for diagnosing pancreatic necrosis 1. Ranson’s score 3 48 hours 2. Apache II illness grading system 10 3. C-reactive protein 120 mg/L 4. Lactate dehydrogenase 270 mg/L 5. Interleukin – 6 Poor accuracy in predicting severity 6. CECT – Gold standard