抗生素课件课件(英文精品) ANTIBIOTIC.pptVIP

ANTIBIOTIC PROBLEM there are many chemicals that are lethal to bacteria (e.g. cyanide), but cannot be used to cure because they are lethal to the host as well problem is to find substances that attack a metabolic pathway found in bacterium but not in host SOLUTION Natural products originally discovered as secretions of fungi or soil bacteria Semi-synthetic products natural products chemically modified in laboratory to improve efficacy of natural product, reduce its side effects Completely synthetic products Treatment of bacteria diseases first known use of antibiotics - ancient C