抗生素英文课件精品 Chemotherapeutic Agents.pptVIP

BIMM118 Chemotherapeutic Agents Antibiotics Antifungals Antivirals Antiprotozoal Antihelmintics Anticancer drugs Antibiotics General Aspects: Principle: inhibit growth of bacteria without harming the host – Drug must penetrate body tissue to reach bacteria (exception: GI infection)(unique targets: cell wall, protein synthesis, metabolic pathways…) Bacteria targeted must be within the spectrum of the AB Drug can be bactericidal or bacteriostatic Different agents can be combined for synergistic effect (Note: not all combinations are useful, e.g. cell wall synthesis inhibitors loose effecti