抗生素英文课件精品——General Outline for Antibiotics.pptVIP

Quinolones Favorable pharmacological attributes Orally administered, quickly absorbed, even with a full stomach Excellent bioavailability in a wide range of tissues and body fluids (including inside cells) Mostly cleared by the kidneys Exceptions are pefloxacin and moxifloxacin which are metabolized by liver Ciprofloxacin, ofloxacin, and pefloxacin are excreted in breast milk “Got Cipro?” Therapeutic Uses of Quinolones Urinary tract infections Prostatitis STD’s Chlamydia Chancroid Not syphilis or gonorrhea (due to increased resistance) Therapeutic Uses of Quinolones GI and abdominal Trav