抗生素与细胞膜(英文课件)Antibiotics and cell envelope.pptVIP

* Polymyxin B binds lipid A phospholipids disrupts outer membrane, Gram negative bacteria toxic to human cells Daptomycin * Causes depolarization of bacterial cell membrane * Isoniazid and Ethionamide - chemically related - blocks mycolic acid synthesis Ethambutol blocks arabinogalactan synthesis Cycloserine Anti-tuberculosis drugs * * * * * * * * * * * * * * * * * * * * * * * * * Dr. Alvin Fox Antibiotics: cell envelope,Lecture 36 * Key Words Sterilization/disinfection/antisepsis Beta lactam Antibiotic Penicillins Selective toxicity Cephalosp