(精编)acute liver failure教学课件.pptVIP

* * * * * * * * Thank you! * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * KCH Criteria Patients with paracetamol toxicity pH 7.3 (7.25 if given NAC) Or all three of the following: Prothrombin time?100s Serum creatinine?level 300 μmol/l Grade III or IVencephalopathy Other patients Prothrombin time 100 seconds orThree of the following variables: Age 10 yr or 40 yr Jaundice 7 days before encephalopathy PT 50s Bilirubin 300mmol/L Positive predictive value for ICU death without transplantation of 0.98 Negative predictive value of 0.82 KCH Criteria Treatment Intensive care of p