2000分子生物改版试卷B.docVIP

2000级医学检验专业分子诊断学考试试卷(B卷) ______________________________________ A1型题（最佳选择题——肯定型） 每一道题有A,B,C,D,E五个备选答案，问题表述形式为肯定陈述，在答题时只需从5个备选答案中选择一个最合适的作为正确答案，并在答卷上将相应题号的相应字母画一条黑粗线。 _______________________________________ 1.What is the major characteristics of neurofibromatosis 2 ? café an lait spots cutaneous or subcutaneous neurofibromas axillary freckling acoustic neuromas and meningiomas E. scoliosis 2.Which is required to activate LPL? apoAⅠ apoCⅠ apoCⅡ apoB48 apoB100 3.Which apo is CM essential? apoAⅠ B. apoAⅡ C. apoB48 D. apoB100 E.apoCⅡ 4.In the procedure of Genomic DNA isolation, which of the following reagent serves to dissolve the cell membrane and denatures proteins? cold phosphate-buffered saline sodium dodecylsufate phenol saturated with 0.5M Tris-HCl dialysis buffer chloroform 5. To evaluate if a neonate has infected HIV, which of the following methods are usually be used? ELISA agglutilation PCR Wester-blot immunofluorescence staining 6. Which RNA can be transferred into mRNA? hnRNA RNAi scRNA sRNA snRNA 7. DNA fragment and DNA probes are to southern blotting as ( ) are to Northern blotting . A. DNA fragments and RNA probes B. RNA fragments and DNA probes C.RNA fragments and RNA probes D. protein fragments and RNA probes E. protein fragments and DNA probes 8.Which is the smallest densist lipoproteins? A.CM B.VLDL C.LDL D.HDL E.IDL 9.Transfer of nucleic acids by vacunm blotting is more efficient than capillary transfer and has been reported to result in a ( ) increase in final hybridization singal obtained. one-to tow fold tow-to three fold one-to three fold three-to four fole tow-to four fold 10.What disorder is spinal muscular atrophy? A.centralnervoussystemdisorder B. autosomal-recessive disorder C.endocrinesystemdisorder D.autosomal-dominant disorder