IPC对动脉血灌注的效果正常人.docVIP

IPC对动脉血灌注的效果：正常人、跛行患者、血管移植患者的比性研究 Effects of intermittent pneumatic compression of the calf and thigh on arterial calf inflow: A study of normals, claudicants, and grafted arteriopaths Konstantinos T. Dells, MD, Phi), Marc J. w. Husmann, MD, NickJ. Cheshire, MD, FRCS, andAndrew N. Nicolaides, MS, FRCS, London United Kingdom Background. Recent data indicate that intermittent pneumatic compression (IPC) of the foot may offer benefits in patients with intermittent claudication exceeding those of standard medications approved by the Food and Drug Administration. IPC of the foot (IPCfoot] and calf (IPCcalf) increases flow velocity in infrainguinal arterial bypass grafts and thus may preveht arterial thrombosis. Our aim was to evaluate the acute effects of IPC of the thigh (IPCthigh), IPCcal[, and 1PC of the thigh and calf (IPCcalf+ thigh) in healthy controls, claudicants, and arteriopaths who have undergone infrainguinal bypass grafting for critical or subcritical limb ischemia. Methods. Sixteen limbs of normals (group A ), 17 limbs of claudicants (group B), and 16 limbs of arteripaths (group C) who had undergone infrainguinal autologous reoascularization were studied. Blood flow was measured in the limbs of normals and claudicants in the popliteal artery and in the grafts of revascularid limbs by using duplex ultrasonography. Mean velocity (reV), peak systolic velocity, end diastolic velocity (EDV), pulsatility index (PI), and volume flow (Q) were measured in the sitting position at rest and within 10 seconds from the delivery of lPCthigh, IPCcalf and IPCcalf + thigh, IPC was delivered at maximum inflation and deflation pressures of 120 mmHg and 0 mm Hg, respectively; inflation and deflation times of 4 and 16 seconds, respectively; and a proximal inflate delay of I second (calf compression preceding that of thigh). Results. In all 3 groups with all IPC modes, the mV, and EDV increased while PI decreased (P .05). IPCthigh was less effective than IPCcalf but still incre