颈动脉狭窄RCT结果解读培训课件.pptVIP

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颈动脉狭窄RCT结果解读培训课件.ppt

颈动脉狭窄的RCT结果解读;Carotid stenosis is present in 75% of men and 62% of women 65 years OLeary DH, Polak JF, Kronmal RA, et al. Stroke 1992; 23: 1752-60 According to the American Heart Association and American Stroke Association 170,000 CEA are performed annually in the USA The risk of developing stroke within 90 days of a transient ischemie event (TIA) is 10.5 %. The mortality rate of Cardiovascular and Cerebrovascular disease was NO 1 in 2008. Johnston SC, Gress DR, Browner WS, Sidney S. JAMA 2000;284:2901 -6. WoIfPA, DAgostino RB, Kannel WB, et al. JAMA 1988;259:1025-9. ;History of Carotid Surgery Carotid Angiogarphy 1927;History of Carotid Surgery Extracranial artery disease – Intracranial lesion;History of Carotid Surgery Carotid Endarterectomy;Famous clinical trials for CEA;Indications of CEA for symptomatic patients (NASCET, ECST) ;North American Symptomatic Carotid Endarterectomy Trial (NASCET);Early CEA is associated with improved outcomes;European Carotid Surgery Trial ;Indications of CEA for asymptomatic patients (ACAS, ACST);ACAS trial; ACST trial;Thrombendarterectomy versus Eversion Endarterectomy EVEREST Trial ;;;Synthetic Patch vs. Venous Patch;Locoregional versus General anesthesia;Management of atherosclerotic carotid artery disease: Clinical practice guidelines of the Society for Vascular Surgery J-Vasc-Surg.2008;48(2):480-6;;Effect of carotid artery stenting;Some completed and ongoing randomized clinical trials;;;The last and biggest RCT for CEA and CAS;;Conclusion:;However, something will be happened like this:;In Stent Restenosis ;In Stent Restenosis;Restenosis on Carotid;;

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