3.0t磁共振灌注加权成像与扩散张量成像在脑胶质瘤分级诊断中应用价值 word格式.docxVIP

that of the rrCBV of peritumoral regions (P﹤0.01).④ The threshold of rrCBF, rrCBV, ADC of solid region of tumors were 2.749,3.058 and 13.95×10-10m2/s respectively, and the diagnosis sensibility were 87%, 91.3% and 81.8% respectively, and the specificity were 100%, 95.5% and 91.3% respectively. All of rrCBF, rrCBV, ADC of solid region of tumors showed high diagnosis accuracy.Conclusion: The threshold of rrCBF, rrCBV, ADC of solid region of tumors were 2.749, 3.058 and 13.95×10-10m2/s respectively, are beneficial to differentiate high and low grade gliomas. Threshold values can be used in clinical setting to evaluate tumors for histological grade of cerebral glioma preoperatively.Key words: Glioma; Magnetic resonance imaging (MRI); Diffusion tensor imaging (DTI); Perfusion-weighted imaging (PWI)英文缩写英文缩略词表英文全称中文全称MRIMagnetic resonance imaging磁共振成像FLAIRFluid attented inversion recovery液体衰减反转恢复DTIDiffusion tensor imaging扩散张量成像PWIPerfusion weighted imaging灌注加权成像rCBFReginal cerebral blood flow局部脑血流量rCBVReginal cerebral blood volume局部脑血容量ADCAverage diffusion coefficient平均扩散系数FAFractional anisotropy各向异性分数Gd-DTPAGadopentetate Dimeglumine钆喷酸葡胺SE-EPISpin echo-echo planar imaging自旋回波平面回波脉冲成像GRE-EPIGradient echo-echo planar imaging梯度回波平面回波脉冲成像FOVField of view视野NEXNumber of excitation激励次数ROCReceiver operating characteristic受试者操作特征分析AUCArea under curve曲线下面积ROIRegion of interest感兴趣区One-wayOne-way analysis of variance单因素方差分析ANOVAMVDMicrovessel density微血管密度ASLArterial spin labeling动脉自旋标记BOLDblood oxygenation level dependent血氧水平依赖DCE-MRIDynamic contrast enhanced MRI动态对比增强 MRISPIOSuperparamagnetic iron Oxide超顺磁性氧化铁独创性声明本人声明所呈交的学位论文是我个人在导师指导下进行的研究工作及取得的 研究成果。尽我所知，除文中已经标明引用的内容外，本论文不包含任何其他个 人或集体已经发表或撰写过的研究成果。对本文的研究做出贡献的个人和集体， 均已在文中以明确方式标明。本人完全意识到，本声明的法律结果由本人承担。学位论文作者签名： 日期：年月日学位论文版权使用授权书本学位论文作者完全了解学校有关保留、使用学位论文的规定，即：学校有 权保留并向国家有关部门或机构送交论文的复印件和电子版，允许论文被查阅和 借阅。本人授权华中科技大学可以将本学位论文的全部或部分内容编入有关数据 库进行检索，可以采用影印、缩印或扫描等复制手段保存和汇编本学位论文。本论文属于保密□ ，在年解密后适用本授权书。不保密□。（请在以上方框内打√）学位论文作者签名：指导教师签名：日期：年月日日期：年月