新生儿肺动脉高压管理课件篇.pptVIP

表面活性物质的应用 随机对照实验的Meta 分析 降低气胸危险 降低需要ECMO的危险 对总体的死亡率没有影响 用药方式有争议 多次用药* 持续输入^ 稀释后灌洗° *Lotze 1998, ^Findlay 1996, ° Wiswell 2002 * Should we give Surfactant (mainly for MAS)? Term or near term newborns may have surfactant deficiency, inactivation, or both Large multicenter study- use of surfactant (if used early) reduced need for ECMO NOT without risk- should be reserved for severe cases, and potentially done at an ECMO center * 血管扩张剂 for PPHN ET1 sildenafil milrinone bostentan Prostacyclins + + * Nitric Oxide- an endogenously produced gas- a treatment for PPHN * 一氧化氮 指征：OI 25 大型随机实验：iNO 对ECMO 的