麻疹(英文)推荐.ppt

* Temp ℃ Days 1-14 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Clinical periods Prodromal stage Exanthem stage Convalescent stage Coryza and conjunctivitis Koplik’s spots Rash Cough Branny desquamation hyperpigmentation Summary of typical clinical features 41 40 39 38 37 36 * DIVISION OF INFECTIOUS DISEASE AND GASTROENTEROLOGY Clinical manifestations Atypical manifestations * DIVISION OF INFECTIOUS DISEASE AND GASTROENTEROLOGY Clinical manifestations Atypical manifestations Mild measles Measles in adults Severe measles Occurs in the patient with partial immunity Occurs in the patients with immunocompromised * DIVISION OF INFECTIOUS DISEASE AND GASTROENTEROLOGY Complications * DIVISION OF INFECTIOUS DISEASE AND GASTROENTEROLOGY Complications Pneumonia Subacute sclerosing panencephalitis (SSPE) Encephalitis Laryngitis Exacerbation of tuberculosis Malnutrition and Vitamin A deficiency the most frequent complication of measles (1) Primary pneumonia (2) Secondary pneumonia * DIVISION OF INFECTIOUS DISEASE AND GASTROENTEROLOGY Lab studies * DIVISION OF INFECTIOUS DISEASE AND GASTROENTEROLOGY Lab studies The white blood cell count tends to be low with a relative lymphocytosis. Multinucleated giant cells can be demonstrated in smears of the nasal mucosa during the prodromal stage. Testing of specific IgM in serum Measles virus isolation * DIVISION OF INFECTIOUS DISEASE AND GASTROENTEROLOGY Diagnosis * DIVISION OF INFECTIOUS DISEASE AND GASTROENTEROLOGY Diagnosis Epidemiologic data Clinical data Laboratory data * DIVISION OF INFECTIOUS DISEASE AND GASTROENTEROLOGY Diagnosis Epidemiologic data Age Season History of contact with patient History of inoculation * DIVISION OF INFECTIOUS DISEASE AND GASTROENTEROLOGY Diagnosis Clinical data Prodromal period Exanthem period Convalescent period Koplik’s spots Typical rash; correlation of rash and fever; catarrh Branny desquamation and brownish discolorati