最新刘力教授治疗溃疡性结肠炎的临床经验研究.pdf

中文摘要 目的：总结导师刘力教授治疗溃疡性结肠炎(UC)的学术思想和临床经验，并通过 临床研究评价导师临床经验方溃结2 号治疗UC 脾虚湿盛证患者的临床疗效及可能的 作用机理，为UC 的治疗提供新思路、新方法。 方法：通过系统整理中医古籍中与UC 有关的论述，广泛收集刘力教授治疗UC 的 临证资料，结合跟师出诊、导师授课的心得体会，总结刘力教授治疗UC 的学术思想 和临床经验。 选取符合溃疡性结肠炎脾虚湿盛型纳入标准的患者69 例，均来自2012 年9 月至 2013 年 9 月陕西中医学院附属医院专家门诊病人，并按照随机、对照的原则将受试 对象分为治疗组和对照组。其中治疗组35 例给予口服溃结2 号方水煎剂治疗，对照 组34 例给予口服美沙拉嗪肠溶片治疗。4 周为 1 个疗程，连续观察2 个疗程。观察 两组的临床疗效及安全性。 结果：按照随机、对照的原则将经诊断标准、纳入标准、排除标准筛选的69例合 格受试对象随机分为两组，治疗组与对照组分别为35例、34例。治疗组临床总有效率 为94. 29%，对照组总有效率为82.35%，治疗组的治愈率明显高于对照组（P 〈0.05）， 随访显示其远期疗效好。 结论：导师经验方溃结2 号方能显著的改善脾虚湿盛型溃疡性结肠炎的临床症状， 具有疗效好，副作用少的特点，是治疗脾虚湿盛型溃疡性结肠炎的安全、有效方剂。 关键词：溃疡性结肠炎；溃结1 号方、溃结2 号方；临床经验研究 3 Chinese abstract Objective: to summarize tutor professor LiuLi treatment of ulcerative colitis (UC) academic thoughts and clinical experience, and the evaluation of clinical research mentor clinical experience and supervising junction 2 treatment of pixu UC wet fill the patients clinical curative effect and possible mechanism of action, for the treatment of UC to provide new ideas and new methods. Methods: through the system in the collating of TCM ancient books related to UC, widely collect LiuLi treatment of UC, a professor of clinical data, combined with visits, teacher teaching experience, summarized professor LiuLi treatment of UC academic thoughts and clinical experience. Select type ulcerative colitis wet pixu (spleen deficient) is filled into the standard of 69 cases of patients, all from September 2012 to September 2013, shaanxi college of traditional Chinese medicine affiliated hospital expert outpatient service patient, according to the principle of randomized, controlled subjects divided into treatment group and control group. Treatment group 35 cases give oral ulcers and 2 water decoction treatment, 34 cases were given oral beauty salad oxazine enteric-coated metformin hydrochloride