基因名称-汕头大学.DOCVIP

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基因名称-汕头大学

第一批反映汕头大学生命科学与医学科学研究优势与特色,候选克隆疾病相关或功能基因列表 No 基因名称全称实验材料 主要功能 提 1 羟基类固醇脱氢酶/羰基还原酶 (HSD/CR,Hydroxysteroid dehydrogenase/carbonyl Reductase ) 发光杆菌(Photobacterium ) 催化类固醇激素类化合物的六元环上的碳的羟化,是类固醇激素降解的关键酶。 课题组 2 鞭毛蛋白A(flagellin core protein A, flaA) 霍乱弧菌(Vibrio cholerae) 弧菌鞭毛蛋白质,是重要的表面抗原。 课题组 3 烷烃羟化酶(Particulate alkane hydroxylases, alkB) 红球菌(Rhodococcus) 降解烷烃的第一步关键酶 课题组 4 Fe-氢酶(Fe-Hydrogenase) 阪崎肠杆菌(Enterobacter?sakazaki) 负责催化产氢 课题组 5 环羟基化双加氧酶大亚基(ring-hydroxylating dioxygenase large subunit) 红球菌(Rhodococcus) 降解多环芳烃的关键酶 课题组 6 麦芽糖孔蛋白前体蛋白(Maltoporin precursor,LamB) 溶藻弧菌(Vibrio alginolyticus) 麦芽糖孔蛋白是一个和麦芽糖-糊精的输送有关的孔蛋白。 课题组 7 polygalacturonase-inhibitingprotein , PGIP) 水稻(或小麦) 该蛋白专一性地抑制真菌内切多聚半乳糖醛酸酶活性,促进植物体内寡聚半乳糖醛酸积累,从而可以有效地阻断真菌侵染过程和抑制相应病害的发生 生物系课题组 8 水稻 该酶为植物淀粉合成的关键酶,它与水稻种子内的脂氧合酶(LOX) 密切相关。 生物系课题组 9 生物系课题组 10 生物系课题组 11 生物系课题组 12 副溶血弧菌 与细菌的免疫和致病性有关 生物系课题组 13 副溶血弧菌 与细菌的免疫和致病性有关 生物系课题组 14 课题组 15 生物系课题组 16 生物系课题组 17 ABCA5(ATP-binding cassette, sub-family A (ABC1), member 5) 食管癌等肿瘤细胞系 ATPase activity, nucleotide binding The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. 医学院课题组 18 ABCC5(ATP-binding cassette, sub-family C (CFTR/MRP), member 5) 食管癌等肿瘤细胞系 ATPase activity, coupled to transmembrane movement of substances 课题组 19 ABLIM1(actin binding LIM protein 1) 食管癌等肿瘤细胞系 cytoske

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