【传染病学课件】cholera.pptVIP

Cholera outbreak archives 6 March 2006Cholera in southern Sudan 29 July 2005Cholera in West Africa 、 Niger 、 Senegal 、Afghanistan 3 December 2004Cholera in Nigeria 、Chad 、Cameroon 、Mozambique 、Zambia 、Mali 、Benin。 20 November 2003Cholera in Liberia 、Mozambique 、Congo 、South Africa 、Mozambique 、Uganda 、Iraq 、Zambia 、C?te dIvoire 15 November 2002Cholera in Democratic Republic of the Congo 、Liberia 、Malawi 、Burundi 、Mozambique 3 December 2001Cholera in Nigeria 、in West Africa 、Chad 、India 、Afghanistan 、Tanzania 、South Africa 、Somalia 、the Federated States of Micronesia 、 Madagasca 。 8 March 2000Cholera in Madagascar BACKGROUND 7th cholera epidemic responsible V. cholerae O1 began in 1961 in Celebes (Sulawesi), Indonesia. Bangladesh in 1963, India in 1964, and the USSR, Iran and Iraq in 1965-1966. In 1970 invaded West Africa, most of the continent involved. In 1991 struck Latin America, Within the year spread to 11 countries. Map of the 7th cholera epidemic(Fig.1) Cholera is making a journey around the world A tough trip The poor guy is continuing on his way around the world The rebellion serogroup  V. cholerae O139 Before 1992, only V. cholerae serogroup O1 caused epidemic cholera Late that year, however, large outbreaks of cholera began in India and Bangladesh caused by unrecognized serogroup of V. cholerae O139, synonym Bengal (virulence, symptom). Spread to 11 countries in South-East Asia. Definition Cholera is an acute watery diarrheal disease caused by vibrio cholerae, serogroup O1 or O139, which occurs both sporadically and as large outbreaks. (shape1,2) most infected people appear as: mild cases carriers participating in the spread of disease. Etiology Filippo Pacini (1812-1883) an Italian physician and anatomist was first to discovered Vibrio cholerae In1854. in intestinal mucosa taken from cholera deaths at autopsy. His findings were ignored by the scientific community.