心血管疾病中药材循证应用的最新进展英文.pptVIP

17th Oct 2006 Disposition Pathways ofDrugs and Chinese Herbal Medicines Challenges for Herbal Clinical trials Dosage formulation: standardized or individualized? Biomarkers? Safety profiles? Pharmacokinetics data? Herbal medicines as multi-component therapeutics It is possible to integrate PK and PD for herbal medicines. Challenges: multi-component therapeutics? Which marker compounds to measure? How to determine therapeutic window? Herb-Drug Interactions: Underestimated Patients: 70% do not reveal their herbal use to their doctors/pharmacists in Western countries Legal issue: rig