二甲双胍对人子宫内膜癌细胞增殖作用的干预分析-intervention analysis of metformin on proliferation of human endometrial carcinoma cells.docxVIP

下载本文档

12
0
约4.9万字
约 46页
2018-06-04 发布于上海
举报

二甲双胍对人子宫内膜癌细胞增殖作用的干预分析-intervention analysis of metformin on proliferation of human endometrial carcinoma cells.docx

二甲双胍对人子宫内膜癌细胞增殖作用的干预分析-intervention analysis of metformin on proliferation of human endometrial carcinoma cells

ABSTRACTObjective：ToobservetheeffectofMetforminonexpressionofREDD1(regulatedin developmentandDNAdamageresponses-1)inhumanendometrialcarcinomacelllinesIshikawacellinvitro,andtheroleofpossibleREDD1/mTORsignaling pathway(independentofAMPKpathway),toinvestigatethepotentialeffectof REDD1onproliferationofhumanendometrialcarcinomacells.Methods:HumanendometrialcarcinomaIshikawacellswererecoveried,andculturedinahumidifier5%CO2incubatorat370C.TheRPMI1640mediumcontained10%fetalbovineserum(FBS).Inoculatingthecellsinto25cm2culturebottlewith5x105cells eachbottlewhenthecellsconfluenced.Themediumwaschangedeve

您可能关注的文档

文档评论（0）

1亿VIP精品文档

更多 >

二甲双胍对人子宫内膜癌细胞增殖作用的干预分析-intervention analysis of metformin on proliferation of human endometrial carcinoma cells.docxVIP