宝安地区泌尿生殖系统衣原体和支原体感染及耐药情况调查.docVIP

宝安地区泌尿生殖系统衣原体和支原体感染及耐药情况调查 　　【摘要】目的:探讨衣原体、解脲支原体和人型支原体在非淋菌性尿道炎(NGU)中的致病作用及其对抗生素的敏感情况。方法:对700例STD门诊及妇科门诊疑似NGU的患者进行衣原体抗原检测、支原体培养及12种抗生素药敏试验。结果:700例患者中衣原体(CT)阳性率为5.6%,支原体培养阳性率为28.3%。支原体阳性的病例中UU感染占80.3%,MH感染占4.3%,UU+MH混合感染占15.2%。支原体对12种抗生素敏感性强力霉素、交沙霉素与美满霉素最为敏感,敏感率分别为:78.8%、57.6%、54.5%。结论:本地区NGU治疗应以强力霉素和交沙霉素为主。? 　　【关键词】衣原体;支原体;非淋菌性尿道炎;药物敏感测定? 　　 　　doi:10.3969/j.issn.1006-1959.2010.08.023文章编号:1006-1959(2010)-08-2003-02? 　　Baoan District urogenital chlamydia and mycoplasma infection and drug resistance survey Liao Hui-ling,Zou Shui-ping,Wang Jin-di ,Yang Jie,Huang Zhi-ming,Gu Xiao-ming,LI Ji,1.Baoan District,Shenzhen City,Guangdong Province,Shiyan preventive health care Hospital;2.Baoan District,Shenzhen Hospital for Chronic Diseases;3.Shiyan,Baoan District,Shenzhen Hospital? 　　【Abstract】Objective:Chlamydia,Ureaplasma urealyticum and Mycoplasma hominis in non-gonococcal urethritis (NGU) in pathogenicity and antibiotic sensitivities.Methods:700 cases of STD clinics and gynecology clinics of patients suspected of NGU Chlamydia antigen,mycoplasma culture and antibiotic susceptibility test of 12.Results:Of the 700 patients,chlamydia (CT) positive rate was 5.6%,mycoplasma culture positive rate was 28.3%.UU positive cases of mycoplasma infection accounted for 80.3%,MH infection accounted for 4.3%,UU+MH mixed infection accounted for 15.2%.Mycoplasma sensitivity to 12 antibiotics doxycycline,josamycin and minocycline is most sensitive,sensitive rates were:78.8%,57.6%,54.5%.Conclusion:The treatment of NGU in this region should doxycycline and josamycin based.? 　　【Key words】Chlamydia;Mycoplasma;Non-gonococcal urethritis;Drug sensitivity determination 　　 　　非淋菌性尿道炎(NGU)是一种较常见的性传播疾病(STD),其主要病原体为衣原体(CT)和支原体(UU/MH)。由于近年发病率不断升高,加上临床滥用抗生素现象严重,致耐药性报道不断增加。为了解深圳市宝安地区STD门诊和妇科门诊患者CT、UU/MH感染及耐药??况,我们对700例疑似NGU的患者进行了CT快速免疫荧光法检测,UU/MH培养,并对UU/MH阳性标本进行了药敏试验,现报告如下:? 　　 　　1.对象和方法? 　　 　　1.1对象:700例患者均为宝安区所属三家医院2008年1月~2009年12月STD门诊及妇科疑似NGU患者,男256例,女444例,年龄16~67岁,病程10天~8月。患者就诊时均有不同程度的自觉症状且取材