维生素C催化合成阿司匹林条件研究.docVIP

维生素C催化合成阿司匹林条件研究 　　[摘要] 目的:以维生素C为催化剂、水杨酸为原料、醋酐为酰化剂,合成阿司匹林。方法:采用乙酰化法合成。结果:初步确定了合成条件,温度为80℃,反应时间为40 min,维生素C用量为0.2 g,收率为56.8%。结论:本方法可行,合成条件需进一步完善。 　　[关键词] 维生素C;合成条件;阿司匹林;研究 　　[中图分类号]R914.5 [文献标识码] A[文章编号] 1673-7210(2009)07(c)-058-02 　　 　　Condition investigation on the synthesis of Aspirin by vitamin C catalyst 　　NIE Xin, WENG Mingtu, CUI Jianqing, XU Zhenqun, HOU Weile 　　(School of Medicine, Foshan University, Foshan 528000, China) 　　[Abstract] Objective: To synthesize Aspirin by using vitamin C as the catalyst, salicylic acid as the raw material and acetic anhydride as the acylating ag