贵阳市8097例乙肝五项标志物检测结果调查报告.docVIP

贵阳市8097例乙肝五项标志物检测结果调查报告 　　【中图分类号】R512 【文献标识码】A 【文章编号】1672-3783(2010)06-0142-03 　　 　　【摘要】目的:为了解贵州省贵阳市普通健康体检人群的HbsAg携带率和抗-HBs水平状况,完善贵阳市乙肝免疫策略以及为防控方案提供支持。方法:收集武警贵州总医院和贵阳市妇幼保健院2009年1-11月体检人员乙肝五项的检测结果,对乙肝发病情况通过表格按年龄、性别分布进行统计,同时分析贵阳市17周岁以下儿童乙肝接种疫苗后阳性感染情况。用Excel 2000建立数据库。用描述性分析的方法分析贵阳市2009年乙肝的流行病学特征及儿童乙肝疫苗预防效果。结果:HBsAg携带率为2.51%,单项抗- HBs阳性率为 36.40%,HBV感染率为10.32%。贵阳市自1992年在0-14岁儿童中推广使用乙肝疫苗以来:17岁以下儿童HBsAg携带率只有0.39%,HBV感染率为0.71%.尤其0-7岁儿童HBsAg阳性率随年龄的减小而快速下降。17岁人群HBsAg阳性率呈缓慢上升趋势,说明普遍接种疫苗的显著预防效果。然而,年龄组HBsAg阳性率曲线高峰后移,且抗-HBs阳性率则呈波浪式变化,提示加强接种疫苗的重要性。接种乙肝疫苗是控制乙肝传播的有效措施,因此,建立并完善贵阳市乙肝免疫管理制度,不断巩固免疫成果,使人群抗体保持在较高的水平上,才是切实阻断HBV传播的关键所在。 　　【关键词】乙肝病毒;乙肝疫苗;感染率;感染模式;儿童免疫 　　【Abstract】Objective:In order to understand and evaluate, the Guiyang City, Guizhou Province, general population health examination to bring the rate of HbsAg and anti-HBs levels of status, improve the Guiyang City, for the prevention and control of hepatitis B immunization strategies and programs to provide support.Methods:Collection of the CAPF Guizhou Hospital and Guiyang City, Maternal and Child Health Hospital in 2009 from January to December 5 medical personnel hepatitis B test results, the incidence of hepatitis B through the tables by age, gender distribution statistics, simultaneous analysis of Guiyang City, hepatitis B vaccination of children under 17 years of age vaccine-positive infection. To establish a database using Excel 2000. Descriptive analysis of Guiyang City in 2009 to analyze the epidemiological characteristics of hepatitis B and hepatitis B vaccine in children, preventive effect.Results:HBsAg carrier rate of 2.51%, anti - HBs positive rate was 36.40%, HBV infection rate was 10.32%. Guiyang City in 1992, 0-14 year olds, has been promoting the use of hepatitis B vaccine: children under 17 years of age HBsAg carrier rate of only 0.39%, HBV infection rate was 0.71%. In particular, 0 - 7-year-old HBsAg-positive rate for children age the decrease of rapid decline. “positive rate of 17-year-old children i