云南的农村的血压和左心室的粒量的关系武阳丰.ppt

Association of Blood Pressure with Left Ventricular Mass in Untreated Hypertensives in Rural Yunnan Province云南的农村的血压和左心室的粒量的关系 A Akasheh, Y Wu武阳丰, Y Li李易, LD Dustin, ND Wong, JM Gardin, SP Azen, RC Detrano狄家诺. China Prevalence of Hypertension in China中国高血压的患病率 Methods方法 Study Sample Design:研究采样 Random cluster sampling to select 10 villages 随机抽样10村子 50 residents between the ages of 50 and 70 years from each village。每个村子50人 490 men and women. 490人 344 available, without other confounding vascular disease (stroke, MI, severe valve disease)344接受探访的（没有脑梗没有心肌梗） Methods方法 Smoking, alcohol use, medication use, hypertension, hyperlipidemia, and diabetes.抽烟喝酒服药高血脂糖尿病的病历 Blood pressure measured three times三次量血压 Height and weight.身高体重 Methods方法 Cardiac Ultrasound -- Philips Optigo portable ultrasound, 2-5 megahertz transducer. Parasternal long axis view.心脏超声波（Philips Optigo)2-5MHz 探头，胸骨旁心长轴 End-diastolic 舒张期 Inter-ventricular septal wall thickness (IST)心室隔厚度 Left ventricular posterior wall thickness (PWT)心左室后壁厚度 Left ventricular diastolic internal diameter (LVID) 心左室内径 Four measurements each 四个测量 Devereux Formula Devereux 公式 LVM (g) = 0.8 x 1.04 [(IST + LVID + PWT)3 - ( LVID)3] + 0.6. Methods方法 Average of 3 SBP and DBP measurements. 三个收缩压和三个舒张压的测量的平均值 Average four estimates of LVM.四个心左室测量的平均值 Calculate left ventricular mass index: LVMI = LVM/BSA.心左室指数 368 participants consented.368 参与者同意 7 excluded because of past stroke or myocardial infarction.7个中风和心肌梗除外 9 (2.4%) excluded because of ongoing medical treatment for hypertension.9个服降压药治疗除外 8 excluded because of inadequate ultrasound images.8个超声波图像不清楚除外 344 participants not undergoing treatment for hypertension344 名无服降压药的参与者 LVMI and Blood Pressure (SBP and DBP) Adjusting for Covariates (age, gender, BMI)心左室粒量指数和血压条件共变量（年龄性别BMI) Coefficient (SE) p Model 1 SBP （收缩压） 0.379 (0.043) 0.0001 Age 0.322 (0.195) 0.10 BMI 0.904 (0.411) 0.03 Male Gender 5.890 (2.179) 0.0