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and dermatitis8yto students20103湿疹课件
Contact Dermatitis Atopic Dermatitis Eczema Clinical features* Management* Contact Dermatitis Acute or chronic inflammatory reactions to substances that come in contact with the skin. Irritant contact dermatitis (ICD) is caused by a chemical irritant Allergic contact dermatitis (ACD) by an antigen (allergen) that elicits a type IV (cell-mediated or delayed) hypersensitivity reaction. Irritant Contact Dermatitis ICD is caused by exposure of the skin to chemical or other physical agents that are capable of irritating the skin, acutely or chronically. The hands are the most commonly affected area Mostly occupational accidents. Epidemiology ICD is the most common form of occupational skin disease, accounting for up to 80% of all occupational skin disorders. Occupational Exposure Individuals engaged in the following occupations/activities are at risk for ICD: housekeeping; hairdressing; medical, dental, and veterinary services; cleaning; floral arranging; agriculture; horticulture; forestry; food preparation and catering; printing; painting; metal work; mechanical engineering; car maintenance; construction; fishing. Most Common Irritant/Toxic Agents Detergent: Soaps, waterless hand cleaners Acids and alkalis: hydrofluoric acid, cement, chromic acid, phosphorus, ethylene oxide, phenol, metal salts. Industrial solvents: coal tar solvents, petroleum, chlorinated hydrocarbons, alcohol solvents, ethylene glycol ether, turpentine, ethyl ether, acetone, carbon dioxide, DMSO, dioxane, styrene. Plants: Euphorbiaceae (spurges, crotons, poinsettias, machneel tree). Racunculaceae (buttercup), Cruciferae (black mustard), Urticaceae (nettles), Solanaceae (pepper, capsaicin), Opuntia (prickly pear). Others: fiberglass, wool, rough synthetic clothing, fire-retardant fabrics, NCR paper. ICD Clinical features Any one can have With clear border Resolved after removing of causative agent Usually acute and can have bulla Allergen Contact Dermatitis Eczematous dermatitis
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