医技学院（华盛顿医疗手册培训器官移植）PPT课件.pptVIP

Chronic Allograft Dysfunction accounts for the vast majority of late graft losses; mediated by immune and nonimmune factors slowly progressive, insidious; major obstacle to long-term graft survival Pathologic characterization：gradual vascular and ductal obliteration, parenchymal atrophy, and interstitial fibrosis Diagnosis: often difficult and generally requires a biopsy Treatment: if established, no effective therapy; require a second solid organ transplant; aimed at prevention Company Logo Graft Rejection General Principles Diagnosis Manifestations Treatment -----Chronic Allograft D