神经论文 学习及记忆.doc

题目：学习与记忆研究进展 作者姓名：XX 学号：XXXX 单位：XXXX大学XXXXXXX学院 XXXXXX 摘要：学习记忆是一个极其会引起中枢神经系统一系列生理生化的改变记忆研究集中于、特殊激素的作用学习记忆与中枢神经系统神经递质代谢有关记忆的形成和保持与海马神经元长时程突触增强效应（Long-term , LTP）有关长期记忆通过细胞核特殊 RNA结构的变化得以经久保存中枢胆碱系统、多巴胺系统一氧化氮学习记忆特异基因脑区系统激素Abstract Learning and memory is a complicated process, causes the central nervous system, a series of physiological and biochemical changes. Current research hotspot of learning and memory in the brain mainly focused on some specific area, some special hormone or neuropeptide role. Learning and memory, and central nervous system neurotransmitter metabolism, memory formation and maintain and cultured hippocanlpal neurons was enhanced synaptic potentiation, (mutually - for LTP), long-term memory is through the nuclei particular structure change of RNA to wear preservation, Central choline system, the dopamine system, nitric oxide, Ca2 + concentrations within the cell such CaMK, Ⅱ neuropeptide, hormone, etc. To nerve receptor has influence of learning and memory, The different brain regions of different specific duties, responsible for coordination in cooperation to complete the process of learning and memory also influences the independent learning and memory. Keywords Learning and memory, Specific genes, Brain systems, Hormone, neuropeptide 目录 前言………………………………………………………5 1 学习与记忆神经生物学研究的历史 ………………? 遗传和个体发育对记忆的作用 ……………………PACAP ………………………………………6 2．2 基因nov …………………………………………6 2．3 海马新基因N4 …………………………………7 2．4 即刻早期基因 …………………………………7 2．5 神经生长因子 (NGF)基因 ……………………7 3 参与学习与记忆的不同脑区系统 …………………………………………………………………8 3．2 纹状体边缘区 …………………………………8 3．3 海马………………………………………………8 3．4 MrD ………………………………………………9 3．5 前额叶(prefrontal corte,PF) ……………9 激素对学习记忆的影响 …………细胞内Ca2+浓度和CaMK…………………9 4．2 神经肽 …………………………………………10 4．2．1 下丘脑神经肽 ………………………………10 4. 2．2 神经下丘脑激素 ……………………………10 4．2．3 垂体肽类 ……………………………………10 4．3 神经递质 ……………………………………11 4．3．1 神经递质 …………………………………11 4．3．2 胆碱能受体 ………………………………11 4．4 激素类……………………………………………11 4．5 ＮＯ………………………………………………11 4．6 其他因素 …………………………………………11 总结与展望…