Artery Stritch School of Medicine大动脉医学Stritch医学课件.ppt

* * * * * * * * * Histology for PathologyCirculatory System Theresa Kristopaitis, MD Associate Professor Director of Mechanisms of Human Disease Kelli A. Hutchens, MD, FCAP Assistant Professor Assistant Director of Mechanisms of Human Disease Loyola Stritch School of Medicine OBJECTIVES 1. Given a histologic section of a large or medium sized artery, identify the a) tunica intima b) tunica media c) tunica adventitia 2. Identify the following structures in a histologic section of an artery a) Endothelium b) Internal elastic lamina c) External elastic lamina d) Vasovasorum 3. Distinguish the characteristics which separate large, medium and small arteries and arterioles. 4. In a tissue section, distinguish a medium sized artery from a medium sized vein 5. In a tissue section identify capillaries, describe their structure and function 6. Compare and contrast general structural features of the arterial vs venous system 7. Describe the structure and function of a lymphatic vessel Vessel Types Arteries Large artery Medium artery Small artery Arteriole Veins Large Vein Medium Vein Small Vein Venule Capillaries Continuous Fenestrated Discontinuous Three layers (tunica) Tunica intima(inner most layer) Endothelium Subendothelium Internal elastic lamina (IEL) in arteries Tunica media Smooth muscle layer External elastic lamina (EEL) in arteries Tunica adventitia (outer most layer) Connective tissue and fibroblasts Longitudinal smooth muscle in veins Vasovasorum in large vessels Overall Structure of Vessels Structure of Vessels a = tunica intima - endothelial lining plus thin layer of underlying connective tissue called the subendothelium. b = tunica media - alternating layers of elastic membranes (elastic lamina) and smooth muscle. c = tunica adventitia - fairly dense connective tissue carrying small blood vessels, the vasa vasorum Large Artery a b c Endothelium Subendothelium Elastic fibers Vasa vasorum High Power of AortaTunica Media Endothelium End