(ppt)脂肪肝与代谢综合征.ppt

脂肪肝与代谢综合征  ;;1998;WWW./nut/db_bmi.htm; ;肥胖和代谢综合征诊断的种族差异;NAFLD的全球化发展趋势;中国成人脂肪肝的患病率;中国成人脂肪肝患病率增高;上海宝钢职工脂肪肝流行趋势1995-2002;队列人群NAFL的消长;基线BMI及其改变与NAFL发生的关系;基线BMI及其改变与NAFL消退的关系;中国普通成人脂肪肝的患病率; 上海市成人脂肪肝的患病率及其病因分布;上海市成人代谢紊乱与脂肪肝的关系;? ? 组 别 ;NAFLD的基本概念;非酒精性脂肪性肝病 -临床病理综合征-;;细胞因子（TNF- α);NASH;单纯性脂肪肝与肝硬化Dam-larsen S, et al. Scand J Gastroenterol 2005;40:460-7;;Lancet 1999;353;15:1634;预测NASH和进展性纤维化的判断模型;香港华人慢性肝病的病因谱;Etiology of fatty liver in Shanghai liver clinic;Clinical features of NAFLD;Hong Kong Chinese with NAFLD 124 ;Normal (38%);Clinical-pathological feature of NAFLD in Chinese ;;NASH肝纤维化的进展速度;影响NAFLD寿命的因素Matteoni Ca, et al. Gastroenterology 1999;116:1413-19;伴肝酶增高的NAFLD患者 生存与死因分析;影响NAFLD寿命的因素Adams LA, et al. Gastroenterology 2005;129:113-21;影响NAFLD预后的因素; 肥胖症;;A: Central obesity B: IFG C: Low HDL-C D: Hypertriglyceridemia E: Hypertension;NAFLD患者随访6年代谢紊乱的发病率; NAFLD与代谢综合征关系密切; NAFLD：2型糖尿病和动脉硬化早期信号;NAFLD的临床意义;动脉硬化;治疗目标;NAFLD的诊疗对策;NAFLD的治疗对策; ;nBqjdZH83*3RS2T+TkK7MSi2F8qR4cUU$pKcft!Z!gOx6B-5Jxt3WXbhjAGe7-sOyGMZv076KpiRWGw1kI$7f5()g6m%e+TJDMZM9E#s#MJM-)-FXWSSClCN1eoTqcFIof!0!weA2KwzZ9tCdKE$3nD2EnHExT-%U!ImR*dNKMv+kq0nq!7Nhz%cD+Ii*uL(YMwcc7G-K69#s7vV7DzrEXBb9HyCIJP22Vf19IG6ag!ZqmgIIm251PMDyaMiqA#poMII2+Hgvk9zDAipf-(Gww546Ph!VnxGcQ)#2HsjjHB%iX+Cx+t+k*zkikCC8RM(GZzgGJ4tDZNZycQfVCQJB7uM$vmGA-RQN7RU0mde18+vWNBtO$EI+$+rYIgwtg21xQMWEI0PWkivEKAPyzcBiW!N5p8YvX3CxK)lL(iNze7LEnD!IBy)YSVMNhKLak6XEZxK6DqOp6x*6#w$**eYMXIy7$DAredy1+EOADZmPa76c1crpWUbpnmQnFmJzRe+ihi+wr+YSe0t26eZBGj+hFERjQnkBk*G%DHl6eFVBe3Kk%OhfD7m93ZQ0rxCunQ#y-lqGcXCpvSN8(loGab+OdDI9fso4MuLPFDpMO5uXw*$liV2KUFBVFO9LmawJ3*)-Kx*HJyzT7sna5-liqBv(1wYRIsPWN83sG)c-(JjceBwxKhEvqhnm7b2WZk!k3HL3Mdvka(Me(OhFx391G68+KQkv+0SAODy(C2gZKw9W#L-MCj$ERNs6RW#t*6Dbcxf$)F3qK8rEzqO5hM!cFnEtQV#k*$O8gh1z!56vOoLbVL9%aWT-m9Fi-xvgesvly1Te108o+(aJUHNls-hSPXx*Aj-JWSC7%ZZ5Frbf3XjDZseIIv!oYASyd%Z4lw90hj$$xZGns)Ey