纤维化疾病的治疗讲座PPT课件.pptVIP

Therapy for Fibrotic Diseases ;Fibrotic Diseases ;how tissue injury and repair lead to fibrosis;目; ;;;;本身也是固有免疫 应答的感应器;01;;;;SOURCES OF FIBROGENIC CELLS; In a new study,injury or stress to endoderm- or mesoderm-derived epithelium,or injury to mesoderm -derived endothelium or myocytes,can lead to increased fibrosis, or fibrogenesis, independent of injury to or recruitment of other cells such as leuko --cytes.these cells signal via paracellular mechanism to neighboring mesenchymal cells . ;;;;THERAPIES FOR FIBROSIS;; 困难; Although success in treatin