义务教育12-2.pptVIP

12.5 Reactions of Amines Weve already seen the two most important reactions of alkylamines: alkylation and acylation. As we saw in the previous section, primary, secondary and tertiary amines can be alkylated by reaction with alkyl halides. Primary and secondary (but not tertiary) amines can also be acylated by nucleophilic acyl substitution reactions with acid chlorides or acid anhvdrides (Sections 10.6 and 10.7) to give amides. tertiary amine 12.6 Heterocyclic Amines Although less basic than typical alkylamines, pyridine (pKb = 8.75) is nevertheless used in a variety of organic reactions