Pharmacological treatment of acute amp; chronic Rhinitis急性和慢性鼻炎的药物治疗；.ppt

下载文档 降价啦

2
0
约8.12千字
约 32页
2018-06-24 发布于浙江
举报
版权申诉
保障服务

Pharmacological treatment of acute amp; chronic Rhinitis急性和慢性鼻炎的药物治疗；.ppt

1、本文档共32页，可阅读全部内容。
2、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。
3、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。

Pharmacologicaltreatmentofacute

4- Cromolyn Mast cell stabilizer (prevent release of histamine other mediators from mast cells) Intranasal cromolyn= useful particularly when given before (1 to 2 weeks) contact with allergen Multiple daily dosing of cromolyn = required Effects: Reduces nasal pruritus, sneezing, rhinorrhea and congestion * Shabana Pharmacological treatment of acute chronic Rhinitis RHINITIS An inflammation swelling of mucous membrane of the nose ?? ???????? ??? ??? ??????? ???? ????????? ??????????? ????? ??? Symptoms of Rhinitis Runny nose, sneezing, itchy nose/eyes stuffiness ?????? Causes of Rhinitis Most common Cold allergies ----Attack may be precipitated by inhalation of an allergen (dust, pollen, animal dander) Types of Rhinitis Acute Rhinitis Short lived ???? ????? ?????; results from viral infections + other causes (allergies) Symptoms= runny nose, sneezing, congestion, post nasal drip, cough low grade fever Cont… ii) Chronic Rhinitis Long- standing Usually occur with chronic sinusitis (chronic rhinosinusitis) Chronic rhinitis is usually an extension of rhinitis caused by inflammation or an infection It may also occur with disease (syphilis ??????, tuberculosis, leishmaniasis ??? ???? ?? ??????? ????? rhinosporidiosis ??? ????) Pathogenesis of Allergic Rhinitis Treatment of Rhinitis?? ??? ???? ????? ???????? Non-pharmacological therapy Avoidance of irritants Dusting/vacuuming ???; washing of bed sheets Intake of fluids Rest Surgery Cont…. Pharmacological therapy 1- Antihistamines (H1 receptor antagonists) 2- ?-Adrenergic agonists 3- Corticosteroids 4- Cromolyn ??????? ??????? ??? ( ?? ?????? ??????? ??????? ) 5- Antibiotics (not relieve symptoms of allergic rhinitis) Antihistamines Agents block the actions of histamine Classical antihistamines = H1 receptor antagonists Histamine Biologically active amine functions as neurotransmitter; Synthesized from histidine ??? ??? ????? Distributed in mast cells, basophils, neurons of brain, cells of stomach Histamine re