质谱Mass Spectrometry－ICP-MS.pptVIP

Mass Spectrometry Mass Analyzer ICP－MS分析性能 测定对象：绝大多数金属元素和部分非金属元素 检测限：1?10-5(Pt) ~ 159(Cl) ng/mL 分析速度： 20 samples per hour 精度：RSD 5% 离子源稳定性：优良的长程稳定性 自动化程度：从进样到数据处理的全程自动化和远程控制 应用范围：地质、环境、冶金、生物、医药、核工业 可测定同位素的比率 Elemental Mass Spectrometry Inorganic Mass Spectrometry Atomic Mass Spectrometry Atomic Source ICP-MS(电感耦合等离子体） GDMS（辉光放电） MIP-MS （微波等离子体） LIMS （激光电离） SNMS （二次中子） SSMS （火花电离） SIMS （二次离子） 火花源(Spark) 针对金属合金属或离子残渣样品等非挥发性无机物的分析，类似于AES中的激发光源。 过 程：30kV 脉冲电压火花样品局部高热元素蒸发原子或离子经加速进入磁场进行分离, 10-30A 特 点：元素分析灵敏度高，可分析复杂样品(60种元素)、谱图简单、线性范围 Mass Analyzers Fourier Signal Analysis:If you had multiple ions of the different mass in the cell, they would all be spinning with similar orbital radii but different frequencies. Thus, the overall signal coming out of the cell is actually a composite signal (a superposition) of all of the cyclotron frequencies of all of the ions present. A good analogy for this is to think of the individual m/z ratios of the ions we are looking at as the keys of a piano. Any one key has a frequency that corresponds to the cyclotron frequency of one of our ions. If you hit just one key at a time, our brains can pick out exactly which key is being pressed. On the other hand, if you took a large hammer and suddenly smashed the keyboard of the piano, this act will set all of the strings vibrating, as though we had hit all of the keys at once. Then we get a loud burst of sound, but our brains will not be able to pick out exactly which of the keys were “hit” at a given time. However, using a computer and the mathematics of Fourier transform methods, we can deconvolute the overall signal to display exactly which frequencies were contributing to the total signal. ??????????????????????????????????????????????????????????????????????????? ????????????????????????????????????????????????????????????????????????? In terms of our mass spectrometer, what we do first is “slam shut the door to the keyboard” by accelerating all the ions with an RF s