免疫方法控制肺病毒感染.pptVIP

Control of Avian Pneumovirus (TRT) infections by Vaccination 免疫方法控制家禽肺病毒感染 Control of Avian Pneumovirus(TRT) Infections by Vaccination TRT病毒引起的疾病Diseases caused by TRT virus 不同的亞型The different virus types 在肉雞的控制Control in broilers 在蛋雞及種雞的控制Control in layers and breeders 免疫方法控制家禽肺病毒感染Control of Avian Pneumovirus(TRT) Infections by Vaccination The different virus types Control in broilers Control in layers and breeders Bacteria Associated With APV Infections Escherichia coli Bordatella spp Alcaligenes faecalis Moraxella spp Pasteurella spp Pseudomonas ORT APV in Laying Turkeys 雞的APVAPV in Chickens 誘導抗体應達 Induces an antibody response 在呼吸道複制 Replicates in respiratory tract 幼齡雞的疾病 Disease in young chickens 細菌常混合感染 Bacteria are complicating agents 以靜脈注射可複制產蛋雞產蛋下降 Production drop in layers reproduced with IV challenge APV偶而可在雞群中分离到 APV occasionally isolated from chickens 有良好的現場証據 Good field evidence APV 首先在雞報導時是稱腫頭綜合症 SHS SHS in chickens at time APV was first reported 雞APV 免疫有經濟效益 APV vaccines beneficial in chickens 免疫方法控制家禽肺病毒感染Control of Avian Pneumovirus(TRT) Infections by Vaccination The disease(s) caused by TRT virus 不同的亞型The different virus types Control in broilers Control in layers and breeders APV分离株間的交叉中和性Cross Neutralisation Between APV Isolates 單克隆抗体中和試驗Neutralisation Tests With Monoclonal Antibodies Cross Neutralisation Between Avian Pneumoviruses Neutralisation Tests Using TRT Monoclonal Antibodies 從火雞及雞分离的APVAPV Isolates from Turkeys and Chickens 病毒不同嗎？Are the viruses “different”? 是否要不同的疫苗呢？Is a different vaccine required for each? 從火雞及雞的APV分离株APV Isolates from Turkeys and Chickens 無抗原性差異 Not antigenically different 在不同品種中生長不同 Variations in growth in each species 生物特性不同 Different biological behaviour 不需要不同的疫苗 (以后) Do not need different vaccines (later) APV 滅活苗 APV Vaccines - Inactivated Nobilis RT inac. 用于雞 For chickens 用于蛋雞及種雞 For use in layers breeders 可以 Can be given by:- 皮下及肌注接種 subcutaneous or intramuscular rou