离子液体催化合成苯甲酸甲酯的的研究.docVIP

石家庄学院毕业论文 PAGE 2 1 -毕 业 设 计（论 文）毕 业 设 计（论 文）题 目：离子液体催化合成苯甲酸甲酯的研究院 系：化工学院专 业：制药工程班 级：姓 名：学 号：指导教师：2015年3月22日 PAGE II离子液体催化合成苯甲酸甲酯的研究【摘要】 HYPERLINK /lemma/ShowInnerLink.htm?lemmaId=151429ss_c=ssc.citiao.link \t _blank 苯甲酸甲酯，又名 HYPERLINK /lemma/ShowInnerLink.htm?lemmaId=151429ss_c=ssc.citiao.link \t _blank 安息香酸甲酯，是一种重要的化工原料，可作为 HYPERLINK /lemma/ShowInnerLink.htm?lemmaId=262279ss_c=ssc.citiao.link \t _blank 有机合成中间体、溶剂和香料，也可用于食品工业中。目前，工业上合成苯甲酸甲酯的主要方法是用浓硫酸作催化剂，该方法存在设备腐蚀严重、副反应多等缺点。本课题以苯甲酸和甲醇为原料，离子液体（吡啶和浓硫酸）为催化剂，对苯甲酸甲酯的合成进行研究。通过进行正交实验，探究催化剂的使用量，原料酸醇摩尔比，反应温度，反应时间对酯化反应产率的影响。实验结果表明，苯甲酸和甲醇的摩尔比为1：5，离子液体用量占总重10%，反应时间为4小时，温度为70℃时，苯甲酸甲酯的产率达到 76.8%。与传统催化剂浓硫酸相比，离子液体作为催化剂具有更好的催化效果。【关键词】离子液体；催化剂；合成；苯甲酸甲酯；产率Research on ionic liquids catalyzed synthesis of benzoic acid methyl ester【Abstract】Benzoic acid methyl ester was used as intermediates in organic synthesis, solvent and spices and used in the food industry. Benzoic acid methyl ester is an important chemical raw materials also known as methyl benzoic acid. The industrial use of concentrated sulfuric acid as catalyst for synthesis of methyl benzoate has many side reactions, serious corrosion of equipment etc. The research and study were carried out with benzoic acid and methanol as raw materials, ionic liquids (pyridine and sulfuric acid) as catalyst for the synthesis of methyl benzoate. Through orthogonal experiment to explore the influence about catalyst dosage, molar ratio, reaction temperature, reaction time on the esterification reaction yield. The experimental results show that the highest yield of methyl benzoate reached 76.8% when the molar ratio of benzoic acid and methanol was 1:5, the amount of ionic liquids for a total weight of 10%, reaction time was 4 hours, the temperature was 70 degrees centigrade. Compared with the traditional sulfuric acid catalyst, the catalytic effect of ionic liquid as catalyst has better.【Key Words】Ionic liquids; catalyst; synthesis; benzoic acid methyl benzene; productivity离子液体