上消化道疾病患幽门螺杆菌感染现状分析.docVIP

上消化道疾病患者幽门螺杆菌感染现状分析 　　【摘要】 目的：了解上消化道疾病患者幽门螺杆菌的感染现状，为临床预防和诊治提供依据。方法：选取笔者所在医院2010年1月-2014年12月诊治的890例上消化道疾病患者为研究对象，分析患者幽门螺杆菌总体感染情况，比较幽门螺杆菌感染与性别、年龄的关系。结果：上消化道疾病患者幽门螺杆菌总体感染率为72.2%，男性幽门螺杆菌感染率为79.6%，显著高于女性的65.0%，差异有统计学意义（P0.05）。反流性食管炎患者幽门螺杆菌感染率最低，为60.0%，与浅表性胃炎患者的65.9%相比差异无统计学意义（P0.05）。糜烂出血性胃炎、慢性萎缩性胃炎、消化性溃疡、胃癌患者幽门螺杆菌感染率分别为79.5%、81.6%、94.3%、84.6%，均显著高于反流性食管炎患者，差异均有统计学意义（P中国论文网 /6/viewhtm 　　【关键词】 上消化道疾病； 幽门螺杆菌； 感染 　　中图分类号 R722.17 文献标识码 B 文章编号 1674-6805（2016）21-0139-03 　　【Abstract】 Objective：To understand current status of helicobacter pylori infection in patients with upper gastrointestinal disease，and to provide the basis for clinical prevention and treatment.Method：From January 2010 to December 2014，890 patients with upper gastrointestinal disease treated in our hospital were selected.The overall infection status and each infection status were analyzed.The relationship between helicobacter pylori infection and genders，ages was compared. Result：The overall helicobacter pylori infection rate of patients with upper gastrointestinal disease was 72.2%.The helicobacter pylori infection rate of men was 79.6%，which was significantly higher than 65.0% of women，and the difference was statistically significant（P0.05）.The rate of helicobacter pylori infection was lowest in patients with reflux esophagitis，about 60.0% with no significant difference compared with 65.9% of patients with superficial gastritis.The rates of helicobacter pylori infection in patients with erosive hemorrhagic gastritis，chronic atrophic gastritis，peptic ulcer and gastric cancer were respectively 79.5%，81.6%，94.3% and 84.6%，which were all significantly higher than that of reflux esophagitis patients（P 　　随着人们生活节奏加快，生活压力增大，吸烟和饮食不规律等不良习惯造成上消化道疾病如胃食管反???病、胃炎、胃溃疡和十二指肠溃疡甚至胃癌越来越多，严重影响了人们的生活质量。每年胃癌、消化性溃疡导致全球至少一百万人死亡，胃癌居癌症死亡病因的第二位，幽门螺杆菌与多种上消化道疾病关系密切，是消化性溃疡、胃癌重要的致病因子[1]。我国是幽门螺杆菌感染的高发国家，本文通过调查上消化道疾病患者幽门螺杆菌的感染情况，了解幽门螺杆菌的分布特点，为疾病的预防和诊治提供依据，具体报道如下。 　　1 资料与方法 　　1.1 一般资料 　　选取笔者所在医院2010年1月-2014年12月消化科诊治的890例上消化道