中西医结治疗睑板腺功能障碍性干眼疗效分析.docVIP

中西医结合治疗睑板腺功能障碍性干眼疗效分析 　　[摘要] 目的 评价中西医结合治疗睑板腺功能障碍性干眼的疗效。 方法 将76例（152眼）MGD患者分为西药组44例（88眼）和中西医结合组（结合组）32例（64眼）。西药组用妥布霉素地塞米松眼膏、玻璃酸钠滴眼液和物理疗法治疗，结合组用西药联合黄连温胆汤进行治疗。比较治疗前后两组各项观察指标的变化。 结果 治疗前，两组观察指标差异无统计学意义（P均0.05）。治疗2周，两组观察指标较治疗前均有改善（P均0.05）。治疗4周，结合组与西药组的泪膜破裂时间[分别为：（9.56±1.14）s和（7.41±0.99）s]、角膜荧光素染色[分别为：（0.91±0.29）和（1.56±0.50）]、泪液分泌试验[分别为：（8.30±0.81）mm和（6.72±1.20）mm]、主观症状评分[分别为：（2.58±0.54）和（4.71±0.52）]比较，差异有高度统计学意义（P0.05）。 结论 中西医结合治疗睑板腺功能障碍性干眼安全、有效，其疗效优于单纯西药治疗。 中国论文网 /6/viewhtm　　[关键词] 中西医结合；睑板腺功能障碍；干眼；治疗 　　[中图分类号] R777.34 [文献标识码] B [文章编号] 1673-9701（2016）19-0083-04 　　[Abstract] Objective To evaluate the efficarcy of Chinese and western medicine in treatment of meibomian gland dysfunction（MGD） related dry eye. Methods A total of 76 cases（152 eyes） MGD patients were divided into western medicine group and combined therapy group， 44 cases（88 eyes） and 32 cases（64 eyes），respectively. The western medicine group was treated with tobramycin dexamethasone eye ointment，sodium hyaluronate eye drops and physical therapy. The combined therapy group was treated with Huanglian Wundan decoction combined with western medicine. The observation indexes were compared before therapy and at 2nd， 4th week after therapy. Results Before treatment，the differences of observation indexes between two groups had no statistical significance（P0.05）. At 2nd week after treatment， the observation indexes were both better（P0.05）. At 4th week after treatment， the BUT， CFS， SⅠt， symptom score were（9.56±1.14）s and（7.41±0.99）s ， （0.91±0.29）and （1.56±0.50）， （8.30±0.81）mm and（6.72±1.20）mm， （2.58±0.54）and（4.71±0.52） for combined therapy group and western medicine group， respectively. And the differences of these indexs had statistical significance（P0.05）. Conclusion Chinese and western medicine in treatment of MGD is safe and effective for MGD related dry eye and its curative effect is superior to western medicine treatment. 　　[Key words] Combination of Chinese traditional and western medicine； Meibomian g