不同甲状腺激素水平及131I剂对甲状腺癌患者.docVIP

不同甲状腺激素水平及131I剂量对甲状腺癌患者 　　[摘要] 目的 探讨不同甲状腺激素水平及131I剂量对甲状腺癌患者一次清甲成功率的影响研究，为进一步提高临床治疗效果提供新的资料和思路。 方法 回顾性分析该院于2011年1月―2014年12月收治的甲状腺癌患者69例，所有患者均在外科手术治疗后再行碘治疗，根据不同甲状腺激素水平及131I剂量对患者进行分组，分析不同分组间的一次清甲成功率。结果 促甲状腺激素水平高于30 μIU/mL和131I剂量高于3.7 GBq的甲状腺癌患者一次清甲成功率明显高（P0.05）。 结论 对于甲状腺癌术后患者，碘具有治疗难度低、副作用小、有效率较高等特点，可以在临床上推广使用。对于促甲状腺激素水平高于30 μIU/mL临床效果更佳，131I剂量高于3.7 GBq临床效果满意。 中国论文网 /6/viewhtm 　　[关键词] 甲状腺癌；131I；临床疗效；术后治疗 　　[中图分类号] R736.1 [文献标识码] A [文章编号] 1674-0742（2015）09（a）-0132-03 　　Different levels of thyroid hormone and 131I dose on the success rate of a time Remove all thyroid cancer in patients 　　SHAN Chang-ping， YANG Ya， XIA Chong-sheng 　　Affiliated Hospital of Jining Medical College， Jining， Shandong Province， 272029 China 　　[Abstract] Objective To investigate the different levels of thyroid hormone and 131I dose on the success rate of a time Remove all thyroid cancer in patients， provide new data and ideas in order to improve further clinical effect and cut down poison and side effect. Methods 69 patients with thyroid cancer who were treated in the hospital from December 2014 to January 2011 were retrospectively analyzed. All patients were treated with I after surgical treatment. The patients were divided into different groups according to different thyroid hormone levels and 131I dose. Results The TSH level higher than 30 IU/mL and 131I doses higher than 3.7 GBq thyroid cancer patients once a clear success rate were significantly higher （P0.05）. Conclusion For the patients after thyroid carcinoma surgery， I had the characteristic that easy to treat， fewer side effect， higher efficiency， which is worthy of clinical popularization. The clinical effect of thyroid stimulating hormone levels higher than 30 IU/mL is better， the clinical effect of 3.7 GBq higher than 131I doses is satisfactory. 　　[Key words] Thyroid carcinoma?? 131I； Clinical efficiency； Postoperative treatment 　　甲状腺癌并非常见癌症，但其在内分泌系统肿瘤中属高发病种。甲状腺肿瘤中90%为分化型甲状腺癌，分化型甲状腺癌包括甲状腺乳头状癌、甲状腺滤泡状癌和Hürthle细胞甲状腺癌，