无症状高尿酸血症者关节超声表现进展及其临床意义.docVIP

无症状高尿酸血症患者关节超声表现进展及其临床意义 　　【摘要】 目的：分析?o症状高尿酸血症患者关节超声表现进展及其临床意义。方法：选择2013年7月-2015年7月在佛山市顺德区中医院接受治疗的无症状高尿酸血症患者60例作为观察组，按照血尿酸水平分为观察1组（420～479 μmol/L）和观察2组（480～540 μmol/L），每组30例；另选择同期在本院接受健康体检者50例作为对照组。三组均经由超声检查两侧下肢膝关节、踝关节以及第一跖趾关节，分析检查结果。结果：三组受检者的超声检查结果比较，差异均有统计学意义（P0.05）。随访24个月，观察2组的双边征、肌腱钙化灶发生率均明显高于观察1组，差异均有统计学意义（P中国论文网 /6/viewhtm 　　【关键词】 无症状高尿酸血症； 关节； 超声 　　Progress and Clinical Significance of Joint Ultrasonography in Asymptomatic Hyperuricemia/CAI Xiao-qing，ZHANG Qian-xi，LU Wei，et al.//Medical Innovation of China，2017，14（27）：020-023 　　【Abstract】 Objective：To analyze the progress and clinical significance of joint ultrasonography in asymptomatic hyperuricemia.Method：A total of 60 cases with asymptomatic hyperuricemia from July 2013 to July 2015 treated in Shunde Hospital of Guangzhou University of Chinese Medicine were selected as the observation group and divided into the observation 1 group（420-479 μmol/L）and the observation 2 group（480-540 μmol/L）according to the blood uric acid，30 cases in each group；50 health people accepted health examination in our hospital at the same period were selected as the control group.Both sides of knee joint，ankle joint and the first metatarsophalangeal joint of three groups were detected via ultrasound，and test results were analysed.Result：The ultrasonic examination results of three groups were compared，the differences were statistically significant（P0.05）.After 24 months of follow-up，the bilateral signs and the incidence of calcification in the observation 2 group were significantly higher than those in observation 1 group，the differences were statistically significant （P 　　【Key words】 Asymptomatic hyperuricemia； Joint； Ultrasound 　　First-author’s address：Shunde Hospital of Guangzhou University of Chinese Medicine，Foshan 528300，China 　　doi：10.3969/j.issn.1674-4985.2017.27.006 　　痛?L是临床常见病、多发病，多由高尿酸血症诱发，以尿酸盐结晶在关节内、肾脏、心脏以及骨质等诸多系统及组织沉积导致相应炎性病变，甚至肾损伤、心脑血管病变等为主要临床特点，严重威胁国民生命健康[1-2]。据报道，痛风性关节炎现已成为全世界突出的公共卫生问题，在病变早期多容易发生漏