艾塞那肽联合门冬胰岛素控制血糖效分析.docVIP

艾塞那肽联合门冬胰岛素控制血糖疗效分析 　　[摘要] 目的 分析肥胖症合并2型糖尿病的确诊患者通过应用艾塞那肽注射液联合门冬胰岛素注射液控制血糖和体重指数的临床综合效果，及缩短血糖达标所需的时间。 方法 对我院2014年6月～2015年6月确诊为2型糖尿病且体重指数（BMI）28 kg/m2的住院患者100例，随机分为对照组和观察组；两组基础治疗的方法均为门冬胰岛素注射液连续皮下注射日基础量，对照组在基础治疗的同时给予阿卡波糖片50 mg，每日3次，餐时嚼服；观察组在基础治疗的基础上应用艾塞那肽注射液5 μg皮下注射每日2次。两组均给予监测指端血糖每日8次。患者住院治疗30 d后观察血糖总体控制情况，综合评估疗效。 结果 观察组的治疗后血糖控制总体优于对照组，差异有统计学意义（P中国论文网 /6/viewhtm　　[关键词] 艾塞那肽注射液；门冬胰岛素；阿卡波糖片；2型糖尿病；胰岛素泵 　　[中图分类号] R587.1 [文献标识码] B [文章编号] 1673-9701（2016）06-0029-05 　　Effect analysis on exenatide combined with insulin aspart in blood glucose control 　　YANG Zhiyong 　　Department of Internal Medicine， Datong Huayang Hospital， Xining 810000， China 　　[Abstract] Objectives To analyze the clinical effect of exenatide injection combined with insulin aspart injection in controlling of blood glucose and weight indices and the reaching-standard time of blood glucose among 50 patients with obesity and type Ⅱ diabetes. Methods A total of 100 patients diagnosed as type Ⅱ diabetes with BMI 28 kg/m2 treated in our hospital from June 2014 to June 2015 were selected and randomly divided into the control group and the observation group. Patients in both groups were treated by daily insulin aspart injection continuous and subcutaneous basal therapy. Patients in the control group were additionally given acarbose tablet 50 mg， tid， chewing at meals； while patients in the observation group were additionally given exenatide subcutaneous injection， 5 μg， bid. Blood glucose of patients in both groups were monitored through finger tips for eight times per day. The overall control of blood glucose and curative effect were assessed after 30 days of hospitalization. Results The blood glucose control in general of observation group after treatment was better than the control group， the difference was statistically significant（P 　　[Key words] Exenatide injection； Insulin aspart； Acarbose tablets； Type Ⅱ diabetes； Insulin pump 　　2型糖尿病是常见的代谢性疾病，我国糖尿病患者数目居世界首位，糖尿病给我国造成的的经济负担也逐年上升[1]。其主要发病原因为遗传与环境因素，胰