视听觉区域erp同步性分析与p300实验分析-erp synchronization analysis and p300 experimental analysis in audio-visual areas.docxVIP

I I 中 文 摘 要 正常认知活动需要广泛分布于整个大脑的大量功能区域的整合传导，和彼此 之间相互作用，对于大范围的神经整合来说，神经电信号同步是一种重要的潜在 机制。从实验记录得到的生物信号中，我们能够检测到的相关频率段内的相位同 步。 脑电的同步被认为是脑功能区域整合或绑定的表现，因此，同步研究逐渐成 为当前脑科学研究中最活跃的课题之一。本文从脑电同步的基本原理出发，阐述 了同步的基本思想，同时，从信号分析方法着手，系统的介绍了如何把时域分析、 频域分析、小波分析、希尔伯特分析等经典和现代信号处理方法应用到脑电同步 研究领域，并验证了相关分析和希尔伯特分析在脑电同步分析中的可行性和有效 性。进一步设计视听觉脑功能区域同时认知的脑电实验，应用希尔伯特方法对真 实脑电数据的事件相关电位（ERP）进行同步性量化。得到结论：大脑在感知和 认知事物时，相关的脑区间自动产生了神经活动的同步化。 本文基于 EGI System 200 脑电采集和分析系统，采用经典的 Odd-Ball 实验 模式，对实验各环节参数进行了反复仔细推敲，得到了 ERP 中的 P300 特征波图 形，并对数据进行了分析。 关键词：脑电；同步；相干；希尔伯特；事件相干电位（ERP）；P300 电子科技大学硕士论文 电子科技大学硕士论文 II II ABSTRACT Signal integration, transmission and interaction between brain functional regions will occur during normal perception activities over brain. Synchronization of nervous signals has been proposed as an important mechanism for spread nervous integration. In fact, from the experiment recording of biological signal, phrase synchronization of associated frequency bands can be detected. Synchronous brain activities are considered as being the indicator of the functional binding or integration of the brain. Accordingly, the researches about synchronization have been a hot topic in recent brain research. In this paper, based on the fundamental principles of synchronous activity, we explain primary ideas concerning synchronization. Beginning with conventional signal processing methods, we introduce ways to apply classic and modern signal processing approaches to EEG (electroencephalograph) synchronization study, which encompass time analysis, frequency analysis, wavelet analysis and Hilbert analysis and so on. Moreover, methods, coherence analysis and Hilbert analysis, have been tested in synchronization application. Furthermore, the experiment on visual-audio simultaneous stimulus was designed to acquire real data, and averaged ERP (event-related potential) data were utilized to get the synchronization index by means of Hilbert transform phase method. Finally, the conclusion was drawn: synchronous activity w