缺血性和非缺血性心肌病心源性猝死的预防ppt课件.pptVIP

T. Jared Bunch MD;Conflicts of Interest;0;适于ICD预防心源性猝死的人群比例？OREGON SUD 研究;;;AVID 试验中患者生存率（未校正）;累积风险;MADIT I 试验;心肌梗死患者植入ICD获益的时间依赖性 ;14,609 例 VALIANT 试验 心源性猝死 – 7%;DINAMIT 试验 – 从ICD中获益较少全因死亡;心肌梗死合并左室功能不全者死亡的原因 ;总死亡率;总死亡;DEFINITE 试验;常规治疗的全因死亡率 (%/年);Buxton: Circ, 2002;COMPANION全因死亡;CRT对无症状左室功能不全的影响（1年结果）;MADIT-CRT 研究;QRS≥120;;减少危险因子;Yaggi, H. et al. N Engl J Med 2005;353:2034-2041;0;无症状左室收缩功能不全的流行病学 ;无症状左室收缩功能不全的疾病分布情况 ;鱼肉或鱼油与猝死风险;根本在于基因;心律失常与先天条件 ;ICD适应症;ICD适应症;ICD适应症;CP1255114-20;Thank You Xie Xie ;Congenital LQTS Therapy;DEBUT Study Profile Brugada Syndrome;Stratification of Risk and Prevention of Sudden Death in Hypertrophic Cardiomyopathy;T. Jared Bunch MD;Conflicts of Interest;0;What Proportion Would Have Qualified for Prevention with ICD?OREGON SUD Study;;Comparison with;Survival (Unadjusted) in the AVID Trial;Cumulative risk;The Multicenter Automatic Defibrillator Implantation Trial (MADIT I);Time Dependence of ICD Benefit after MI;14,609 pt VALIANT Trial SCD – 7%;DINAMIT Trial – Lack of Benefit from ICDAll-Cause Mortality;Causes of Death After MI with LV Dysfunction;Total Mortality;Total Mortality;Time Benefit of ICD therapy (DEFINITE Trial);Annual rate of death from any cause with conventional therapy (%);Buxton: Circ, 2002;COMPANIONDeath from Any Cause;Impact of CRT on Asymptomatic Left Ventricular Dysfunction at 12 months;MADIT-CRT;QRS≥120;;Risk Factor Reduction;Yaggi, H. et al. N Engl J Med 2005;353:2034-2041;0;Epidemiology of “Asymptomatic” Left Ventricular Systolic Dysfunction;Underlying Diseases in “Asymptomatic” Left Ventricular Systolic Dysfunction;The consumption of fish and fish oil sudden death risk;All in the Genes;Arrhythmias and Congenital Conditions;Recommendations for ImplantableCardioverter-Defibrillators;Recommendations for ImplantableCardioverter-Defibrillators;Recommendations for ImplantableCardioverter-Defibrillators;CP1255114-20;Thank You Xie Xie ;Congenital LQTS Therapy;DEBUT Study Profile Brugada Syndrome;Str