肺炎球菌和流行性感冒病毒亚单位疫苗欢迎来到ppt课件.ppt

Pneumococcal and Influenza vaccine ;Epidemiology-morbidity/mortality; Under Five Mortality Rates by Provinces of Kenya, KDHS 2008.;Pneumoccocal ;Serotype;Serotype;Polysaccharide vs conjugate;Immunogenecity ;Preventing pneumonia by immunization;Prospect of vaccines;Prevention and Education;PRIORITY GROUP FOR VACCINE;Way forward;References;VIRAL PNEUMONIA;;;Frequent with Influenza A, less for type B, never for type C To escape population immunity Involves the external antigens : HA and NA Two types of mutations depending on whether the RNA segment variation is small or great : Antigenic drift Antigenic shift;Flu spreads across the world and ages ;Seasonal Occurrence of Influenza, RSV and Parainfluenza Viruses, United States,1996-99;Results;Ghendon Y. Influenza - its impact and control Rapp. trimest. sanit. mond. 1992;45:306-11;;Impact of Respiratory Viruses on Illness in Children Aged 5 Years;Clinical Courses of Croup in Finland;Persons 50 years of age, Residents of nursing homes, Adults and children with chronic disorders of the pulmonary or cardiovascular systems, Adults and children with chronic metabolic diseases, renal dysfunction, or hemoglobinopathies ( such as Sickle cell disease), Immunocompromised adults and children, including HIV infected persons and users of immunosuppressive medications Pregnant women belonging to the high-risk groups. Newly recognized: Healthy children aged 6-24 months(5 years)